Hybrid negative enrichment of circulating tumor cells from whole blood in a 3D-printed monolithic device-Reference-Cited by-同舟云学术

Hybrid negative enrichment of circulating tumor cells from whole blood in a 3D-printed monolithic device

Published:2019 Issue:20 Volume:19 Page:3427-3437
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Chu Chia-Heng¹²³⁴^ORCID,Liu Ruxiu¹²³⁴^ORCID,Ozkaya-Ahmadov Tevhide¹²³⁴,Boya Mert¹²³⁴,Swain Brandi E.¹²³⁴,Owens Jacob M.⁵²³⁴,Burentugs Enerelt⁶²³⁴,Bilen Mehmet Asim⁷⁸³⁴⁹,McDonald John F.¹⁰²³⁴¹¹,Sarioglu A. Fatih¹²³⁴⁹^ORCID

Affiliation:

1. School of Electrical and Computer Engineering

2. Georgia Institute of Technology

3. Atlanta

4. USA

5. Wallace H. Coulter Department of Biomedical Engineering

6. School of Chemical & Biomolecular Engineering

7. Department of Hematology and Medical Oncology

8. Emory University School of Medicine

9. Winship Cancer Institute

10. School of Biological Sciences

11. Parker H. Petit Institute for Bioengineering and Bioscience

Abstract

A monolithic 3D-printed microfluidic device integrated with stacked layers of functionalized leukodepletion channels and microfiltration for the negative enrichment of circulating tumor cells directly from clinically relevant volumes of whole blood.

Funder

Georgia Institute of Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2019/LC/C9LC00575G

Reference62 articles.

1. Circulating Tumor Cells in Gastrointestinal Malignancies: Current Techniques and Clinical Implications

2. Enrichment, detection and clinical significance of circulating tumor cells

3. Cancer Metastasis: Building a Framework