Synthesis of α-CF3-proline derivatives by means of a formal (3 + 2)-cyclisation between trifluoropyruvate imines and Michael acceptors-Reference-Cited by-同舟云学术

Synthesis of α-CF3-proline derivatives by means of a formal (3 + 2)-cyclisation between trifluoropyruvate imines and Michael acceptors

Published:2019 Issue:23 Volume:17 Page:5731-5735
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Winter Michael¹²³⁴,Faust Kirill⁵²³⁴,Himmelsbach Markus⁶²³⁴^ORCID,Waser Mario¹²³⁴^ORCID

Affiliation:

1. Institute of Organic Chemistry

2. Johannes Kepler University Linz

3. 4040 Linz

4. Austria

5. Institute of Catalysis

6. Institute of Analytial Chemistry

Abstract

The first (3 + 2)-cyclisation of 3,3,3-trifluoropyruvate-derived imines and indandione-based Michael acceptors giving spirocyclic α-CF₃-α-proline derivatives was developed.

Funder

Austrian Science Fund

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB01134J

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