Chemical profiling and total quality assessment of Isodon japonica using data-independent acquisition mode combined with superimposed multiple product ion UHPLC-Q-TOF-MS and chemometric analysis

Author:

Jin Yiran12345,Tian Tingting12345,Ma Yinghua12345,Hou Ludan12345,Guan Shuai12345,Sun Wenjing12345,Du Yingfeng12345ORCID,Zhang Lantong12345

Affiliation:

1. Department of Pharmaceutical Analysis

2. School of Pharmacy

3. Hebei Medical University

4. Shijiazhuang

5. P. R. China

Abstract

In this paper, a combined analytical strategy was developed and aimed at rapid characterization and quantitation of ent-kaurane diterpenoids in Isodon japonica using UPLC-Q-TOF-MS/MS.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference29 articles.

1. T. T.Cui , L. J.Zhao , Y.Liu and W.Jiang , Toxicological studies on Isodon japonica var. glaucocalyx , Guide. China. Med. , 2010 , vol. 8 , pp. 246–249

2. State Administration of Traditional Chinese Medicine , Chinese materia medica , Shanghai Scientific and Technical Publishers , Shanghai , 1999 , p. 6166 . Chinese

3. Simultaneous quantification of 19 diterpenoids in Isodon amethystoides by high-performance liquid chromatography–electrospray ionization tandem mass spectrometry

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