One-pot two-stage biocatalytic upgrading of biomass-derived aldehydes to optically active β-amino alcohols via sequential hydroxymethylation and asymmetric reduction amination

Author:

Suo Yin-Hua1,Zhang Jing-Qi1,Qi Ning1,Huang Shuang-Ping1,Gao Hang1,Gao Li-Li2,Zhang Chao-Feng1,He Yu-Cai3,Zhang Jian-Dong1ORCID

Affiliation:

1. Department of Biological and Pharmaceutical Engineering, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, Shanxi 030024, China

2. College of Environmental Science and Engineering, Taiyuan University of Technology, Taiyuan, Shanxi 030024, China

3. State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei 430062, China

Abstract

One-pot two-stage biocatalytic upgrading of biomass-derived aldehydes to optically active β-amino alcohols via sequential hydroxymethylation and asymmetric reduction amination.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

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