Using iSUSTAIN™ to validate the chemical attributes of different approaches to the synthesis of tacn and bridged (bis)tacn ligands

Author:

Coghlan C. J.12345,Campi E. M.12345,Jackson W. R.12345,Hearn M. T. W.12345

Affiliation:

1. Centre for Green Chemistry

2. School of Chemistry

3. Monash University

4. Clayton

5. Australia

Abstract

Using green chemistry principles, alternative approaches for the synthesis of commercially important aza-macrocyclic tacn and (bis)tacn derivatives have been investigated to determine the step average and overall efficiency of these synthetic methods.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Reference50 articles.

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2. R. A. Sheldon , I.Arends and U.Hanefeld, Introduction: Green chemistry and catalysis, in Green Chemistry and Catalysis, Wiley-VCH, Weinheim, 2007, pp. 1–47

3. D. J. C. Constable and C. C.Jiménez-Gonzáles, Evaluating the greenness of synthesis, in Handbook of Green Chemistry, ed. C.-J. Li, Wiley-VCH, 2012, vol. 7, pp. 35–67

4. Unification of Reaction Metrics for Green Chemistry:  Applications to Reaction Analysis

5. Unification of Reaction Metrics for Green Chemistry II:  Evaluation of Named Organic Reactions and Application to Reaction Discovery

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