Efficient syntheses of alpha- and beta-C-nucleosides and the origin of anomeric selectivity

Author:

Liu Tongchao12345,Zhu Zhengdan678910,Ren Huanming589104,Chen Yabin589104,Chen Guohua1112134,Cheng Maosheng1234,Zhao Dongmei1234,Shen Jingkang589104,Zhu Weiliang678910,Xiong Bing589104,Chen Yue-Lei589104ORCID

Affiliation:

1. Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education

2. Shenyang Pharmaceutical University

3. Shenyang 110016

4. P. R. China

5. State Key Laboratory of Drug Research

6. CAS Key Laboratory of Receptor Research

7. Drug Discovery and Design Center

8. Shanghai Institute of Materia Medica

9. Chinese Academy of Sciences

10. Shanghai 201203

11. School of Pharmacy

12. China Pharmaceutical University

13. Nanjing 210009

Abstract

Valuable C-nucleosides are efficiently prepared with excellent anomeric selectivity depending on protecting groups on sugar moiety.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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