Discovery of boron-containing compounds as Aβ aggregation inhibitors and antioxidants for the treatment of Alzheimer's disease
Author:
Affiliation:
1. College of Chemical Engineering
2. Zhejiang University of Technology
3. Hangzhou 310014
4. China
5. Institute of Drug Synthesis and Pharmaceutical Process
6. School of Pharmaceutical Sciences
7. Sun Yat-sen University
8. Guangzhou 510006
Abstract
A novel series of boron-containing compounds were designed, synthesized and evaluated as multi-target-directed ligands against Alzheimer's disease.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Guangdong Province
Publisher
Royal Society of Chemistry (RSC)
Subject
Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/MD/C8MD00315G
Reference29 articles.
1. A Century of Alzheimer's Disease
2. Pathological Substrates of Cognitive Decline in Alzheimer’s Disease
3. Cholinesterase Inhibitors and Beyond
4. Pharmacotherapies for Alzheimer's disease: Beyond cholinesterase inhibitors
5. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
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