Engineered nanomicelles targeting proliferation and angiogenesis inhibit tumour progression by impairing the synthesis of ceramide-1-phosphate-Reference-Cited by-同舟云学术

Engineered nanomicelles targeting proliferation and angiogenesis inhibit tumour progression by impairing the synthesis of ceramide-1-phosphate

Published:2024 Issue:21 Volume:16 Page:10350-10365
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Yadav Poonam¹^ORCID,Rana Kajal¹^ORCID,Chakraborty Ruchira¹,Khan Ali²^ORCID,Mehta Devashish²^ORCID,Jain Dolly¹,Aggarwal Bharti¹^ORCID,Jha Somesh K.¹^ORCID,Dasgupta Ujjaini²^ORCID,Bajaj Avinash¹^ORCID

Affiliation:

1. Laboratory of Nanotechnology and Chemical Biology, Regional Centre for Biotechnology, NCR Biotech Science Cluster, 3rd Milestone Faridabad-Gurgaon Expressway, Faridabad-121001, Haryana, India

2. Amity Institute of Integrative Sciences and Health, Amity University Haryana, Manesar, Gurgaon-122413, Haryana, India

Abstract

Tumour cells secrete various proangiogenic factors like VEGF, PDGF, and EGF that result in the formation of highly vascularized tumours with an immunosuppressive tumour microenvironment.

Funder

Council of Scientific and Industrial Research, India

Department of Biotechnology, Ministry of Science and Technology

University Grants Commission

Indian Council of Medical Research

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NR/D3NR04806C

Reference42 articles.

1. The tumor microenvironment and its role in promoting tumor growth

2. Microenvironmental regulation of tumour angiogenesis

3. Exploring the crosstalk between endothelial cells, immune cells, and immune checkpoints in the tumor microenvironment: new insights and therapeutic implications

4. Unraveling the Role of Angiogenesis in Cancer Ecosystems

5. Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges