Reversible polypeptide hydrogels from asymmetric telechelics with temperature-dependent and Ni2+-dependent connectors

Author:

Pham Thao T. H.123,van der Gucht Jasper123,Mieke Kleijn J.123,Cohen Stuart Martien A.123

Affiliation:

1. Physical Chemistry and Soft Matter

2. Wageningen University

3. 6703 HB Wageningen, The Netherlands

Abstract

An asymmetric (‘hybrid’) triblock polypeptide TR4H with two different, orthogonally self-assembling end blocks has been constructed by conjugating a long (37 kDa) random coil block (R4) with a triple helix former T = (Pro-Gly-Pro)9 at the N terminus, and a histidine hexamer (‘Histag’, H) at the C terminus.

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

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