Interaction of the synthetic antithrombotic peptide P10 with thrombin: a spectroscopy study
Author:
Affiliation:
1. Key Lab of Marine Food Quality and Hazard Controlling Technology of Zhejiang Province
2. College of Life Sciences
3. China Jiliang University
4. Hangzhou
5. China
Abstract
Thrombin is a critical serine protease in the coagulation system and is widely used as a target protein for antithrombotics.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA02994J
Reference55 articles.
1. Target Specific Anticoagulant Peptides: A Review
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4. The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited humanα-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships
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