Strontium modified calcium phosphate cements – approaches towards targeted stimulation of bone turnover
Author:
Affiliation:
1. Centre for Translational Bone, Joint and Soft Tissue Research
2. Medical Faculty and University Hospital
3. Technische Universität Dresden
4. Dresden
5. Germany
Abstract
Strontium modified calcium phosphate cements can target local bone turnover by stimulating osteoblast proliferation and differentiation (1) as well as bone mineralisation (2), reducing osteoclastogenesis (3) and resorption activity, increase osteoclast apoptosis (4) and affect osteoblast/osteoclast paracrine signalling (5).
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2015/TB/C5TB00654F
Reference126 articles.
1. Calcium orthophosphates
2. Third-Generation Biomedical Materials
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