Multiparametric modulation of magnetic transduction for biomolecular sensing in liquids

Author:

Sanz-de Diego Elena1,Aires Antonio2,Palacios-Alonso Pablo1ORCID,Cabrera David13ORCID,Silvestri Niccolo4ORCID,Vequi-Suplicy Cinthia C.1,Artés-Ibáñez Emilio J.15,Requejo-Isidro José67,Delgado-Buscalioni Rafael8ORCID,Pellegrino Teresa4ORCID,Cortajarena Aitziber L.129ORCID,Terán Francisco J.17ORCID

Affiliation:

1. iMdea Nanociencia, Ciudad Universitaria de Cantoblanco, 28049 Madrid, Spain

2. CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo de Miramón 194, 20014, Donostia-San Sebastián, Spain

3. School of Pharmacy and Bioengineering, Keele University, Guy Hilton Research Centre, Thurnburrow Drive, ST4 7QB, Stoke on Trent, UK

4. Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genoa, Italy

5. Nanotech Solutions, 40150 Villacastín, Spain

6. Centro Nacional de Biotecnologia (CSIC), 28049 Madrid, Spain

7. Nanobiotecnología (iMdea-Nanociencia), Unidad Asociada al Centro Nacional de Biotecnología (CSIC), 28049 Madrid, Spain

8. Dpto Física Teórica Materia Condensada, Universidad Autónoma de Madrid, 28049 Madrid, Spain

9. Ikerbasque, Basque Foundation for Science, Bilbao, Spain

Abstract

The transducing capacity of magnetic nanoparticles for biomarker detection in AC magnetometry lies in a number of modulating parameters. This is assessed through the variations of AC magnetic hysteresis area in absence (black colour, A0) and presence (violet colour, A) of analytes.

Funder

European Commission

European Cooperation in Science and Technology

Ministerio de Ciencia e Innovación

Consejería de Educación, Juventud y Deporte, Comunidad de Madrid

Publisher

Royal Society of Chemistry (RSC)

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