Multiplexed blood–brain barrier organ-on-chip-Reference-Cited by-同舟云学术

Multiplexed blood–brain barrier organ-on-chip

Published:2020 Issue:17 Volume:20 Page:3132-3143
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Zakharova M.¹²³⁴⁵^ORCID,Palma do Carmo M. A.¹²³⁴⁵,van der Helm M. W.¹²³⁴⁵,Le-The H.¹²³⁴⁵^ORCID,de Graaf M. N. S.⁶⁷⁸⁹^ORCID,Orlova V.⁶⁷⁸⁹,van den Berg A.¹²³⁴⁵^ORCID,van der Meer A. D.¹⁰³⁵⁹^ORCID,Broersen K.¹⁰³⁵⁹,Segerink L. I.¹²³⁴⁵^ORCID

Affiliation:

1. BIOS Lab on a Chip group

2. MESA+ Institute for Nanotechnology

3. Technical Medical Centre

4. Max Planck Institute for Complex Fluid Dynamics

5. University of Twente

6. Department of Anatomy and Embryology

7. Leiden University Medical Center

8. Leiden

9. The Netherlands

10. Applied Stem Cell Technologies

Abstract

The developed multiplexed chip contains 8 channels that can be accessed individually or simultaneously with increased throughput. The visual inspection of cells in the device was improved with our fabricated 2 μm-thick porous PDMS membrane.

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/LC/D0LC00399A

Reference61 articles.

1. L. Hein , K.Mohr and D.Bieger , Color Atlas of Pharmacology , ed. H. Lullmann , 3rd edn, Thieme , 2005

2. Epithelial Barriers in Homeostasis and Disease

3. Breaking Barriers. New Insights into Airway Epithelial Barrier Function in Health and Disease