A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids-Reference-Cited by-同舟云学术

A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids

Published:2014 Issue:6 Volume:14 Page:1198-1205
ISSN:1473-0197
Container-title:Lab Chip
language:en
Short-container-title:Lab Chip

Author:

Ruppen Janine¹²³⁴²,Cortes-Dericks Lourdes⁵⁶⁷⁸²,Marconi Emanuele¹²³,Karoubi Golnaz⁵⁶⁷⁸²,Schmid Ralph A.⁵⁶⁷⁸²,Peng Renwang⁵⁶⁷⁸²,Marti Thomas M.⁵⁶⁷⁸²,Guenat Olivier T.¹²³⁵⁶

Affiliation:

1. ARTORG Lung Regeneration Technologies Lab

2. University of Berne

3. CH-3010 Berne, Switzerland

4. Graduate School for Cellular and Biomedical Sciences

5. Division of General Thoracic Surgery

6. University Hospital of Berne

7. Berne, Switzerland

8. Department of Clinical Research

Abstract

This study reports on a microfluidic platform on which single multicellular spheroids from malignant pleural mesothelioma (MPM), an aggressive tumor with poor prognosis, can be loaded, trapped and tested for chemotherapeutic drug response.

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2014/LC/C3LC51093J

Reference37 articles.

1. Multicellular tumor spheroids: An underestimated tool is catching up again

2. Mammalian Target of Rapamycin Contributes to the Acquired Apoptotic Resistance of Human Mesothelioma Multicellular Spheroids

3. The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance

4. Modeling Tissue Morphogenesis and Cancer in 3D

5. Paper-supported 3D cell culture for tissue-based bioassays

Cited by 91 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Next-generation 3D tumor modeling: A microfluidic platform with biocompatible red carbon dots for live cell imaging in co-cultured elongated spheroid tumor model;Biosensors and Bioelectronics;2024-12

2. Exploring Importance and Regulation of Autophagy in Cancer Stem Cells and Stem Cell-Based Therapies;Cells;2024-06-01

3. Review: 3D cell models for organ-on-a-chip applications;Analytica Chimica Acta;2024-05

4. In-vitro assays for immuno-oncology drug efficacy assessment and screening for personalized cancer therapy: scopes and challenges;Expert Review of Clinical Immunology;2024-04-03

5. Rapid prototyping of PMMA-based microfluidic spheroid-on-a-chip models using micromilling and vapour-assisted thermal bonding;Scientific Reports;2024-02-03