Degradation products of crosslinked silk fibroin scaffolds modulate the immune response but not cell toxicity-Reference-Cited by-同舟云学术

Degradation products of crosslinked silk fibroin scaffolds modulate the immune response but not cell toxicity

Published:2023 Issue:16 Volume:11 Page:3607-3616
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Sapudom Jiranuwat¹^ORCID,Kongsema Mesayamas²,Methachittipan Apipon³,Damrongsakkul Siriporn⁴⁵⁶,Kanokpanont Sorada⁴⁵⁶,Teo Jeremy C. M.¹^ORCID,Khongkow Mattaka⁷,Tonsomboon Khaow⁸,Thongnuek Peerapat⁵⁶⁹^ORCID

Affiliation:

1. Laboratory for Immuno Bioengineering Research and Applications, Division of Engineering, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates

2. Department of Zoology, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand

3. International School of Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok 10330, Thailand

4. Department of Chemical Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok 10330, Thailand

5. Center of Excellence in Biomaterial Engineering for Medical and Health, Faculty of Engineering, Chulalongkorn University, Bangkok 10330, Thailand

6. Biomedical Engineering Research Center, Faculty of Engineering, Chulalongkorn University, Bangkok 10330, Thailand

7. National Nanotechnology Centre (NANOTEC), National Science and Technology Development Agency (NSTDA), Klong Luang, Pathum Thani, 12120, Thailand

8. National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Klong Luang, Pathum Thani, 12120, Thailand

9. Biomedical Engineering Program, Faculty of Engineering, Chulalongkorn University, Bangkok 10330, Thailand

Abstract

The degradation products of crosslinked silk fibroin scaffolds induce distinct macrophage polarization and responses, without causing cytotoxicity or genotoxicity.

Funder

New York University Abu Dhabi

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D3TB00097D

Reference51 articles.

1. A Review of Structure Construction of Silk Fibroin Biomaterials from Single Structures to Multi-Level Structures

2. The Biomedical Use of Silk: Past, Present, Future

3. Silk proteins for biomedical applications: Bioengineering perspectives