Aminations and arylations by direct C–O activation for the design of 7,8-dihydro-6H-5,8-ethanopyrido[3,2-d]pyrimidines-Reference-Cited by-同舟云学术

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Aminations and arylations by direct C–O activation for the design of 7,8-dihydro-6H-5,8-ethanopyrido[3,2-d]pyrimidines

Published:2021 Issue:32 Volume:11 Page:19363-19377
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Laurent Mazarine¹²³⁴⁵,Bostyn Stéphane⁶⁷⁸⁹¹⁰,Marchivie Mathieu¹¹¹²¹³¹⁰,Robin Yves¹⁴¹⁰,Routier Sylvain¹²³⁴⁵^ORCID,Buron Frédéric¹²³⁴⁵^ORCID

Affiliation:

1. Institut de Chimie Organique et Analytique

2. ICOA

3. UMR CNRS 7311

4. Université d’Orléans

5. Orléans

6. Institut de Combustion

7. Aérothermique, Réactivité, et Environnement (ICARE)

8. 1c, Avenue de la Recherche Scientifique

9. 45071 CEDEX 2 Orléans

10. France

11. ICMCB CNRS-UMR 5026

12. Université de Bordeaux

13. Bordeaux

14. ISOCHEM

Abstract

A convenient design of 7,8-dihydro-6H-5,8-ethanopyrido[3,2-d]pyrimidines is reported from quinuclidinone, which afforded versatile platforms that were then used to access a variety of original heterocycles.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA03092B

Reference41 articles.

1. Exploration of the chemical space and its three historical regimes

2. Chemical space as a source for new drugs

3. Exploring Novel Biologically-Relevant Chemical Space Through Artificial Intelligence: The NCATS ASPIRE Program

4. Two‐ and Three‐dimensional Rings in Drugs

5. The Modern Face of Synthetic Heterocyclic Chemistry

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