Synthesis, chemical characterization, and biological evaluation of a novel auranofin derivative as an anticancer agent-Reference-Cited by-同舟云学术

Synthesis, chemical characterization, and biological evaluation of a novel auranofin derivative as an anticancer agent

Published:2022 Issue:35 Volume:51 Page:13527-13539
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Cirri Damiano¹^ORCID,Massai Lara²,Giacomelli Chiara³^ORCID,Trincavelli Maria Letizia³,Guerri Annalisa²^ORCID,Gabbiani Chiara¹^ORCID,Messori Luigi²^ORCID,Pratesi Alessandro¹^ORCID

Affiliation:

1. Department of Chemistry and Industrial Chemistry (DCCI), University of Pisa, Via Giuseppe Moruzzi 13, 56124 Pisa, Italy

2. Department of Chemistry “Ugo Schiff”, University of Florence, Via della Lastruccia 3-13, 50019 Sesto Fiorentino, FI, Italy

3. Department of Pharmacy, University of Pisa, Via Bonanno 6, Pisa 56126, Italy

Abstract

A novel auranofin-inspired compound showed good antiproliferative properties, associated with lower lipophilicity and a faster reactivity, which make this complex have significant pharmaceutical and therapeutic advantages over auranofin itself.

Funder

Associazione Italiana per la Ricerca sul Cancro

Fondazione Cassa di Risparmio di Firenze

Beneficentia Stiftung

Università di Pisa

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/DT/D2DT00836J

Reference71 articles.