Transition-metal-free decarboxylative halogenation of 2-picolinic acids with dihalomethane under oxygen conditions
Author:
Affiliation:
1. State Key Laboratory of Fine Chemicals
2. Dalian University of Technology
3. Dalian 116023
4. China
5. WPI-AIMR (WPI-Advanced Institute for Materials Research)
Abstract
The reaction of 2-picolinic acids with dihalomethane proceeded smoothly via N-chlorocarbene intermediates to afford 2-halogen-substituted pyridines in satisfactory to excellent yields under oxygen conditions.
Funder
National Natural Science Foundation of China
Fundamental Research Funds for the Central Universities
Publisher
Royal Society of Chemistry (RSC)
Subject
Pollution,Environmental Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/GC/C9GC02407G
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