Programmable synthesis of multiply arylated cubanes through C–H metalation and arylation-Reference-Cited by-同舟云学术

Programmable synthesis of multiply arylated cubanes through C–H metalation and arylation

Published:2020 Issue:29 Volume:11 Page:7672-7675
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Okude Ryo¹²³⁴,Mori Genki⁵⁶⁷⁴,Yagi Akiko¹²³⁴^ORCID,Itami Kenichiro¹²³⁴⁸^ORCID

Affiliation:

1. Graduate School of Science

2. Nagoya University

3. Nagoya 464-8602

4. Japan

5. Central Pharmaceutical Research Institute

6. Japan Tobacco Inc.

7. Osaka 569-1125

8. Institute of Transformative Bio-Molecules (WPI-ITbM)

Abstract

Cubane has attracted attention due to its unique 3D structure. Herein, we report the programmable synthesis of multiply arylated cubanes. The developed reaction allows the late-stage and regioselective installation of aryl groups.

Funder

Japan Society for the Promotion of Science

Nagoya University

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC01909G

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