Semi-catalytic reduction of secondary amides to imines and aldehydes

Author:

Lee Sun-Hwa123,Nikonov Georgii I.123

Affiliation:

1. Chemistry Department

2. Brock University

3. St. Catharines, Canada

Abstract

Ruthenium catalyzed reduction of iminoyl chlorides by HSiMe2Ph allows for a two-step conversion of secondary amides into imines and aldehydes.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Reference53 articles.

1. The Amide Linkage: Structural Significance in Chemistry, Biochemistry, and Materials Science , ed. A. Greenberg , C. M. Breneman and J. F. Liebman , John Wiley & Sons , New York , 2000

2. M. Hudlicky , Reductions in Organic Chemistry , ACS monograph, 1996 , vol. 118

3. Modern Reduction Methods , ed. P. G. Andersson and I. J. Munslow , Wiley , NY , 2008

4. J. Seyden-Penne , Reduction by Alumino- and Borohydrides in Organic Synthesis , Wiley , NY , 2nd edn, 1997

5. R. C. Larock , Comprehensive Organic Transformations: a Guide to Functional Group Preparation , Wiley-VCH , NY , 2nd edn, 1999

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