Antibody-functionalized theranostic protein nanoparticles for the synergistic deep red fluorescence imaging and multimodal therapy of ovarian cancer-Reference-Cited by-同舟云学术

Antibody-functionalized theranostic protein nanoparticles for the synergistic deep red fluorescence imaging and multimodal therapy of ovarian cancer

Published:2021 Issue:18 Volume:9 Page:6183-6202
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Borlan Raluca¹²,Focsan Monica²^ORCID,Perde-Schrepler Maria³,Soritau Olga³,Campu Andreea²,Gaina Luiza⁴,Pall Emoke⁵,Pop Bogdan⁶⁷,Baldasici Oana⁸,Gherman Claudia⁹,Stoia Daria²,Maniu Dana¹²^ORCID,Astilean Simion¹²^ORCID

Affiliation:

1. Biomolecular Physics Department, Faculty of Physics, Babes-Bolyai University, Cluj-Napoca, Cluj, Romania

2. Nanobiophotonics and Laser Microspectroscopy Centre, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babes-Bolyai University, Cluj-Napoca, Cluj, Romania

3. Department of Radiobiology and Tumor Biology, Oncology Institute Prof. Dr. Ion Chiricuta, Cluj-Napoca, Cluj, Romania

4. The Research Centre on Fundamental and Applied Heterochemistry, Department of Chemistry, Faculty of Chemistry and Chemical Engineering, Babes-Bolyai University, Cluj-Napoca, Cluj, Romania

5. Department of Infectious Diseases, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Cluj, Romania

6. Department of Pathology, Oncology Institute Prof. Dr. Ion Chiricuta, Cluj-Napoca, Cluj, Romania

7. Department of Pathology, University of Medicine and Pharmacy Iuliu Haţieganu, Cluj-Napoca, Cluj, Romania

8. Department of Functional Genomics, Proteomics and Experimental Pathology, Oncology Institute Prof. Dr. Ion Chiricuta, Cluj-Napoca, Cluj, Romania

9. Department of Functional Genomics, Proteomics and Experimental Pathology, Oncology Institute Prof. Dr Ion Chiricuta, Cluj-Napoca, Cluj, Romania

Abstract

This work presents novel phototheranostic protein nanoagents loaded with a newly synthesized deep red dye, revealing fluorescence imaging, photothermal and photodynamic features simultaneously upon targeted internalization within ovarian cancer cells.

Funder

Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM01002F

Reference55 articles.

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