A novel vertical flow assay for point of care measurement of iron from whole blood

Author:

Serhan Michael12345,Jackemeyer David1234,Abi Karam Karam1234,Chakravadhanula Kasyap1234,Sprowls Mark12345,Cay-Durgun Pinar12345,Forzani Erica12345ORCID

Affiliation:

1. Center for Bioelectronics and Biosensors

2. Biodesign Institute

3. Arizona State University

4. USA

5. School of Engineering for Matter

Abstract

We present a novel vertical flow assay to measure iron levels in whole blood from a finger-prick sample. The system leverages a sensor strip, detection chamber and in-house app that detects color change and outputs iron concentration in five minutes.

Funder

Arizona State University

National Institutes of Health

National Institute of Biomedical Imaging and Bioengineering

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Reference38 articles.

1. L. A. Kaplan and A. J.Pesce , Iron, Porphyrin, and Bilirubin Metabolism , in Clinical Chemistry Theory Analysis and Correlation , St. Louis , Mosby , 1996

2. Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes

3. World Health Organization , Nutritional anaemias: tools for effective prevention and control , Geneva , 2017 edn, 2017

4. Iron Deficiency: Global Prevalence and Consequences

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