Exploring the binding and cleavage activities of nickelII complexes towards DNA and proteins-Reference-Cited by-同舟云学术

Exploring the binding and cleavage activities of nickelII complexes towards DNA and proteins

Published:2021 Issue:15 Volume:45 Page:6693-6708
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Kumar Manish¹²³⁴^ORCID,Lal Neetika⁵²³⁴,Luthra Pratibha Mehta⁵²³⁴,Masram Dhanraj T.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Delhi

3. Delhi-110007

4. India

5. Dr. B.R. Ambedkar Centre for Biomedical Research

Abstract

Three novel nickel(ii) complexes with cis octahedral geometry display excellent binding and cleavage affinity towards DNA and proteins. Furthermore, all complexes show superior cytotoxicity against human lung (A549) and breast (MCF-7) tumor cells.

Funder

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NJ/D0NJ06210C

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1. Challenges and Opportunities in the Development of Organometallic Anticancer Drugs

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