Mitochondria-targeted zirconium metal–organic frameworks for enhancing the efficacy of microwave thermal therapy against tumors

Author:

Zhou Hongqiao1234,Fu Changhui56784,Chen Xiaowei910114,Tan Longfei56784,Yu Jie1213144,Wu Qiong56784,Su Liuhui1234,Huang Zhongbing1234ORCID,Cao Feng1513144,Ren Xiangling56784,Ren Jun56784,Liang Ping1213144ORCID,Meng Xianwei56784ORCID

Affiliation:

1. College of Materials Science & Engineering

2. Sichuan University

3. Chengdu 610065

4. China

5. Laboratory of Controllable Preparation and Application of Nanomaterials

6. CAS Key Laboratory of Cryogenics

7. Technical Institute of Physics and Chemistry Chinese Academy of Sciences

8. Beijing 100190

9. Department of Radiology

10. The First Affiliated Hospital of China Medical University

11. Shenyang 110001

12. Department of Interventional Ultrasound

13. Chinese PLA General Hospital

14. Beijing 100853

15. Department of Cardiology

Abstract

Although microwave (MW) thermal therapy has been widely studied for the treatment of tumors due to its less invasiveness, recurrence of tumors is still observed because of the relatively low bioavailability of MW sensitizers.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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