Enhanced osteogenesis of multilayered pore-closed microsphere-immobilized hydroxyapatite scaffold via sequential delivery of osteogenic growth peptide and BMP-2-Reference-Cited by-同舟云学术

Enhanced osteogenesis of multilayered pore-closed microsphere-immobilized hydroxyapatite scaffold via sequential delivery of osteogenic growth peptide and BMP-2

Published:2017 Issue:41 Volume:5 Page:8238-8253
ISSN:2050-750X
Container-title:J. Mater. Chem. B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Zhang Bing-jun¹²³⁴⁵^ORCID,He Lei¹²³⁴⁵,Han Zhi-wei¹²³⁴⁵,Li Xin-guo¹²³⁴⁵,Zhi Wei¹²³⁴⁵,Zheng Wei⁶⁷⁴⁵,Mu Yan-dong⁸⁹⁴⁵,Weng Jie¹²³⁴⁵

Affiliation:

1. Key Laboratory of Advanced Technologies of Materials (Ministry of Education)

2. School of Materials Science and Engineering

3. Southwest Jiaotong University

4. Chengdu

5. P. R. China

6. Orthopaedic Department

7. General Hospital of Chengdu Military Region

8. Dental Department

9. Sichuan Province People's Hospital

Abstract

Accelerated bone regeneration of a novel microsphere-immobilized hydroxyapatite scaffold based on a sequence of steps regulated by two biofactors; this regeneration occurs through an orchestrated sequence of spatial changes.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2017/TB/C7TB01970J

Reference50 articles.

1. Multifunctional coatings to simultaneously promote osseointegration and prevent infection of orthopaedic implants

2. Biofabrication of bone tissue: approaches, challenges and translation for bone regeneration

3. Bone Tissue Engineering: Recent Advances and Challenges