A multi-modal exploration of heterogeneous physico–chemical properties of DCIS breast microcalcifications-Reference-Cited by-同舟云学术

A multi-modal exploration of heterogeneous physico–chemical properties of DCIS breast microcalcifications

Published:2022 Issue:8 Volume:147 Page:1641-1654
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Gosling Sarah¹^ORCID,Calabrese Doriana²,Nallala Jayakrupakar²,Greenwood Charlene³,Pinder Sarah⁴,King Lorraine⁵,Marks Jeffrey⁵,Pinto Donna⁶,Lynch Thomas⁵,Lyburn Iain D.¹⁷⁸,Hwang E. Shelley⁵,Grand Challenge PRECISION Consortium ,Rogers Keith¹,Stone Nicholas²^ORCID

Affiliation:

1. Cranfield Forensic Institute, Cranfield University, Shrivenham, UK

2. School of Physics and Astronomy, University of Exeter, Exeter, UK

3. School of Chemical and Physical Sciences, Keele University, Keele, UK

4. Division of Cancer Studies, King's College London, Guy's Hospital, London, UK

5. Department of Surgery, Duke University Medical Center, Durham, NC, USA

6. www.DCIS411.com, San Diego, CA, USA

7. Thirlestaine Breast Centre, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, Gloucestershire, UK

8. Cobalt Medical Charity, Cheltenham, UK

Abstract

Combined crystallographic and spectroscopic methods were used to investigate the heterogeneity of breast calcifications found associated with ductal carcinoma in situ, revealing distinctive patterns in protein distribution and mineral composition.

Funder

Cancer Research UK

KWF Kankerbestrijding

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AN/D1AN01548F

Reference43 articles.

1. Breast microcalcifications: The lesions in anatomical pathology

2. Structure and composition of microcalcifications in benign and malignant lesions of the breast: Study by light microscopy, transmission and scanning electron microscopy, microprobe analysis, and X-ray diffraction