Design of ferrocenylseleno-dopamine derivatives to optimize the Fenton-like reaction efficiency and antitumor efficacy
Author:
Affiliation:
1. School of Chemistry and Molecular Engineering
2. Nanjing Tech University
3. Nanjing 211816
4. China
5. Jiangsu Province Institute of Materia Medica
Abstract
The tertiary amine in F4b facilitates the Fenton-like reaction to generate toxic ˙OH which induces apoptosis through CDK-2 inactivation.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA03537A
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