Synthesis and in vitro evaluation of fluorine-18 benzimidazole sulfones as CB2 PET-radioligands-Reference-Cited by-同舟云学术

Synthesis and in vitro evaluation of fluorine-18 benzimidazole sulfones as CB2 PET-radioligands

Published:2019 Issue:20 Volume:17 Page:5086-5098
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Kallinen Annukka¹²³,Boyd Rochelle⁴⁵⁶³,Lane Samuel⁷²³,Bhalla Rajiv⁸⁹³,Mardon Karine⁸⁹³,Stimson Damion H. R.⁸⁹³,Werry Eryn L.¹²³,Fulton Roger⁷²³,Connor Mark⁴⁵⁶³^ORCID,Kassiou Michael¹²³^ORCID

Affiliation:

1. School of Chemistry

2. The University of Sydney

3. Australia

4. Biomedical Sciences

5. Faculty of Medicine and Health Sciences

6. Macquarie University

7. Faculty of Health Sciences

8. The Centre for Advanced Imaging

9. The University of Queensland

Abstract

New ¹⁸F-fluorinated benzimidazole 5-sulfones with low nanomolar binding affinity were synthesised as PET-radioligand candidates for the CB2 receptor.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB00656G

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