Total synthesis and characterization of thielocin B1 as a protein–protein interaction inhibitor of PAC3 homodimer-Reference-Cited by-同舟云学术

Total synthesis and characterization of thielocin B1 as a protein–protein interaction inhibitor of PAC3 homodimer

Published:2014 Issue:5 Volume:5 Page:1860-1868
ISSN:2041-6520
Container-title:Chem. Sci.
language:en
Short-container-title:Chem. Sci.

Author:

Doi Takayuki¹²³,Yoshida Masahito¹²³,Ohsawa Kosuke¹²³,Shin-ya Kazuo⁴⁵,Takagi Motoki⁶⁷⁵,Uekusa Yoshinori⁸⁹¹⁰¹¹¹,Yamaguchi Takumi⁸⁹¹⁰¹¹¹,Kato Koichi⁸⁹¹⁰¹¹¹,Hirokawa Takatsugu¹²⁴⁵,Natsume Tohru⁴⁵

Affiliation:

1. Graduate School of Pharmaceutical Sciences

2. Tohoku University

3. Sendai 980-8578, Japan

4. National Institute of Advanced Industrial Science and Technology (AIST)

5. Tokyo 135-0064, Japan

6. Biomedicinal Information Research Center (BIRC)

7. Japan Biological Informatics Consortium (JBIC)

8. Okazaki Institute for Integrative Bioscience and Institute for Molecular Science

9. National Institutes of Natural Sciences

10. Okazaki, Japan

11. Nagoya City University

12. Computational Biology Research Center (CBRC)

Abstract

We have characterized the inhibition of the protein–protein interaction of the homodimer of proteasome assembling chaperone (PAC) 3 with thielocin B1.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/SC/C3SC53237B

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