Conformational selection underpins recognition of multiple DNA sequences by proteins and consequent functional actions

Author:

Naiya Gitashri1234,Raha Paromita1234,Mondal Manas Kumar5674,Pal Uttam1234,Saha Rajesh1234,Chaudhuri Susobhan8910114,Batabyal Subrata8910114,Kumar Pal Samir8910114,Bhattacharyya Dhananjay5674,Maiti Nakul C.1234,Roy Siddhartha1213144

Affiliation:

1. Division of Structural Biology and Bioinformatics

2. CSIR-Indian Institute of Chemical Biology

3. Kolkata 700 032

4. India

5. Computational Science Division

6. Saha Institute of Nuclear Physics

7. Kolkata 700064

8. Department of Chemical

9. Biological & Macromolecular Sciences

10. S. N. Bose National Centre for Basic Sciences

11. Kolkata 700 098

12. Department of Biophysics

13. Bose Institute

14. Kolkata

Abstract

Multiple DNA sequence recognition through selection from a pre-existing conformational ensemble leading to different outcomes.

Funder

Council of Scientific and Industrial Research

Department of Science and Technology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

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