The uptake, retention and clearance of drug-loaded dendrimer nanoparticles in astrocytes – electrophysiological quantification

Author:

Chowdhury Helena H.12345ORCID,Cerqueira Susana R.678910,Sousa Nuno111281314,Oliveira Joaquim M.678910ORCID,Reis Rui L.678910ORCID,Zorec Robert12345

Affiliation:

1. Laboratory of Neuroendocrinology – Molecular Cell Physiology

2. Institute of Pathophysiology

3. Faculty of Medicine

4. 1000 Ljubljana

5. Slovenia

6. 3B's Research Group – Biomaterials

7. Biodegradables and Biomimetics

8. University of Minho

9. Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine

10. 4805-017 Barco GMR

11. Life and Health Sciences Research Institute (ICVS)

12. School of Health Sciences

13. 4710-057 Braga

14. Portugal

Abstract

Endocytosed dendrimer nanoparticles (NPs) are cleared from the astrocytes by an increased rate of transient exocytotic fusion events.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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