Selective C–H chalcogenation of thiazoles via thiazol-2-yl-phosphonium salts
Author:
Affiliation:
1. Institute of Organic Chemistry and Macromolecular Chemistry
2. Friedrich Schiller University Jena
3. 07743 Jena
4. Germany
Abstract
Medicinally relevant substituted benzothiazoles and thiazoles are prepared under mild conditions by a regioselective C2–H chalcogenation via preparation of the phosphonium salt and the subsequent reaction with S- and Se-centered nucleophiles.
Funder
Carl-Zeiss-Stiftung
Friedrich-Schiller-Universität Jena
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00684J
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1. Benzobisthiazole-Based Semiconducting Copolymers Showing Excellent Environmental Stability in High-Humidity Air
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3. Cruciform π-Systems for Molecular Electronics Applications
4. Rhodium-catalyzed synthesis of unsymmetrical di(aryl/heteroaryl)methanes using aryl/heteroarylmethyl ketones via CO–C bond cleavage
5. Rhodium-Catalyzed Synthesis of Unsymmetric Di(heteroaryl) Sulfides Using Heteroaryl Ethers and S-Heteroaryl Thioesters via Heteroarylthio Exchange
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