Merging hypervalent iodine and sulfoximine chemistry: a new electrophilic trifluoromethylation reagent-Reference-Cited by-同舟云学术

Merging hypervalent iodine and sulfoximine chemistry: a new electrophilic trifluoromethylation reagent

Published:2019 Issue:45 Volume:10 Page:10516-10523
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Kalim Jorna¹²³⁴^ORCID,Duhail Thibaut⁵⁶⁷⁸⁹,Le Thanh-Nghi⁵⁶⁷⁸⁹,Vanthuyne Nicolas¹⁰¹¹¹²¹³¹⁴,Anselmi Elsa⁵⁶⁷⁸⁹^ORCID,Togni Antonio¹²³⁴^ORCID,Magnier Emmanuel⁵⁶⁷⁸⁹^ORCID

Affiliation:

1. Department of Chemistry and Applied Biosciences

2. ETH Zürich

3. 8093 Zürich

4. Switzerland

5. Institut Lavoisier de Versailles

6. UMR CNRS 8180

7. Université de Versailles-Saint-Quentin

8. 78035 Versailles Cedex

9. France

10. Institut des Sciences Moléculaires de Marseille

11. Centrale Marseille

12. UMR 7313

13. Aix-Marseille Université

14. CNRS

Abstract

Two prominent trifluoromethylation reagent classes join forces in a bench stable hypervalent iodosulfoximine CF₃ transfer agent. We report its synthesis, properties and reactivity, opening up new possibilities in trifluoromethylation chemistry.

Funder

Agence Nationale de la Recherche

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC04289J

Reference64 articles.

1. Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

2. Fluorine in Pharmaceuticals: Looking Beyond Intuition