Inhibition of human DNA topoisomerase IB by nonmutagenic ruthenium(ii)-based compounds with antitumoral activity-Reference-Cited by-同舟云学术

Inhibition of human DNA topoisomerase IB by nonmutagenic ruthenium(ii)-based compounds with antitumoral activity

Published:2016 Issue:2 Volume:8 Page:179-192
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

de Camargo Mariana S.¹²³⁴⁵,da Silva Monize M.¹²³⁴⁵,Correa Rodrigo S.¹⁶⁷⁸⁹,Vieira Sara D.¹⁰¹¹¹²,Castelli Silvia¹⁰¹¹¹²,D'Anessa Ilda¹⁰¹¹¹²,De Grandis Rone¹³¹⁴¹⁵¹⁶¹⁷,Varanda Eliana¹³¹⁴¹⁵¹⁶¹⁷,Deflon Victor M.¹⁸¹⁹²⁰²¹⁵,Desideri Alessandro¹⁰¹¹¹²,Batista Alzir A.¹²³⁴⁵

Affiliation:

1. Departamento de Química

2. Universidade Federal de São Carlos

3. CP 676

4. CEP 13565-905

5. São Carlos, Brazil

6. ICEB

7. Universidade Federal de Ouro Preto

8. CEP 35400-000

9. Ouro Preto, Brazil

10. Dipartimento di Biologia

11. Università Tor Vergata di Roma

12. 00133 Rome, Italy

13. Departamento de Ciências Biológicas

14. Faculdade de Ciências Farmacêuticas

15. UNESP

16. CEP 14800-900

17. Araraquara, Brazil

18. Instituto de Química de São Carlos

19. Universidade de São Paulo

20. CP 780

21. CEP 13560-970

Abstract

New cytotoxic ruthenium(ii) compounds with mercaptopyridine derivatives inhibit human DNA topoisomerase IB and interact moderately with DNA and BSA macromolecules.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

São Paulo Research Foundation

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MT/C5MT00227C

Reference75 articles.

1. Potentially cytotoxic new copper(ii) hydrazone complexes: synthesis, crystal structure and biological properties