Coupling partner-dependent unsymmetrical C–H functionalization of N-phenoxyacetamides leading to sophisticated spirocyclic scaffolds

Author:

Song Xia1,Wang Kelin1,Xue Lian1,Yu Haibo2ORCID,Zhang Xinying1ORCID,Lee Richmond2ORCID,Fan Xuesen1ORCID

Affiliation:

1. Key Laboratory for Research and Evaluation of Innovative Drug, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, School of Environment, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China

2. School of Chemistry and Molecular Bioscience and Molecular Horizons, University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia

Abstract

In this paper, a coupling partner-dependent unsymmetrical C–H functionalization of N-phenoxyacetamides leading to the formation of sophisticated spirocyclic scaffolds is presented.

Funder

National Natural Science Foundation of China

Science and Technology Innovation Talents in Universities of Henan Province

Henan Key Laboratory of Organic Functional Molecules and Drug Innovation

National Computational Infrastructure

Australian Research Council

University of Wollongong

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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