Self-assembled PEGylated amphiphilic polypeptides for gene transfection-Reference-Cited by-同舟云学术

Self-assembled PEGylated amphiphilic polypeptides for gene transfection

Published:2021 Issue:39 Volume:9 Page:8224-8236
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Klemm Paul¹²,Behnke Mira¹²,Solomun Jana I.¹²^ORCID,Bonduelle Colin³^ORCID,Lecommandoux Sébastien³^ORCID,Traeger Anja¹²^ORCID,Schubert Stephanie²⁴^ORCID

Affiliation:

1. Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstrasse 10, 07743 Jena, Germany

2. Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany

3. Univ. Bordeaux, CNRS, Bordeaux INP, LCPO, UMR 5629, F-33600, Pessac, France

4. Institute of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, Friedrich Schiller University Jena, Lessingstrasse 8, 07743 Jena, Germany

Abstract

Three biodegradable block copolymers composed of a poly(ethylene glycol) block and a copolypeptide block with varying compositions of cationic l-lysine and hydrophobic benzyl-l-glutamate were designed for gene delivery applications.

Funder

Deutsche Forschungsgemeinschaft

Bundesministerium für Bildung und Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2021/TB/D1TB01495A

Reference65 articles.

1. The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress

2. Gene therapy comes of age