Structures and esterolytic reactivity of novel binuclear copper(ii) complexes with reduced l-serine Schiff bases as mimic carboxylesterases

Author:

Zhang Qin1234,Shu Jun1234,Zhang Yajun56789,Xu Zhigang56789,Yue Jian1234,Liu Xiaoqiang1234,Xu Bin1234,Chen Zhongzhu56789,Jiang Weidong1234ORCID

Affiliation:

1. School of Chemistry and Environmental Engineering

2. Sichuan University of Science & Engineering

3. Sichuan Zigong 643000

4. P. R. China

5. College of Pharmacy

6. National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics

7. Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine

8. Chongqing University of Arts and Sciences

9. Chongqing 402160

Abstract

Three novel binuclear copper(ii) complexes with reduced l-serine Schiff bases exhibited significant activity differences for the hydrolysis of PNPA and PNPP, suggesting a favourable intramolecular nucleophilic pathway for PNPP.

Funder

National Natural Science Foundation of China

Chongqing University of Arts and Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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