A low-temperature, photoinduced thiol–ene click reaction: a mild and efficient method for the synthesis of sugar-modified nucleosides-Reference-Cited by-同舟云学术

A low-temperature, photoinduced thiol–ene click reaction: a mild and efficient method for the synthesis of sugar-modified nucleosides

Published:2017 Issue:43 Volume:15 Page:9226-9233
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Bege Miklós¹²³⁴,Bereczki Ilona¹²³⁴,Herczeg Mihály¹²³⁴^ORCID,Kicsák Máté¹²³⁴,Eszenyi Dániel¹²³⁴,Herczegh Pál¹²³⁴^ORCID,Borbás Anikó¹²³⁴^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry

2. University of Debrecen

3. H-4032 Debrecen Egyetem tér 1

4. Hungary

Abstract

While studying the radical mediated hydrothiolation of nucleoside enofuranosides, an unusual temperature effect was observed by the exploitation of which various thio-substituted nucleoside analogues were produced.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB02184D

Reference42 articles.

1. Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases

2. Sugar-Modified Nucleosides in Past 10 Years, A Review

3. Nucleosides with Modified Sugar Ring: Synthesis and Biological Activities

4. Chemoenzymatic synthesis and in situ application of S-adenosyl-l-methionine analogs

5. Synthesis of 5′-carboxymethylsulfonyl-5′-deoxyribonucleosides under mild hydrolytic conditions: a new class of acidic nucleosides as inhibitors of ribonuclease A

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