Quantitative brain-derived neurotrophic factor lateral flow assay for point-of-care detection of glaucoma-Reference-Cited by-同舟云学术

Quantitative brain-derived neurotrophic factor lateral flow assay for point-of-care detection of glaucoma

Published:2022 Issue:18 Volume:22 Page:3521-3532
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Wu Yue¹²,Hu Yubing¹^ORCID,Jiang Nan³,Anantharanjit Rajeevan²⁴,Yetisen Ali K.¹^ORCID,Cordeiro M. Francesca²⁴⁵⁶^ORCID

Affiliation:

1. Department of Chemical Engineering, Imperial College London, South Kensington, London, UK

2. Department of Surgery and Cancer, Imperial College London, South Kensington, London, UK

3. West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China

4. The Imperial College Ophthalmic Research Group (ICORG), Imperial College London, London, UK

5. The Western Eye Hospital, Imperial College Healthcare NHS Trust (ICHNT), London, UK

6. Glaucoma and Retinal Neurodegeneration Group, Department of Visual Neuroscience, UCL Institute of Ophthalmology, London, UK

Abstract

We develop a quantitative lateral flow assay (LFA) device that is able to measure the tear level of brain derived neurotrophic factor (BDNF). The device shows great potential to serve as an ideal platform for early detection of glaucoma.

Funder

Engineering and Physical Sciences Research Council

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D2LC00431C

Reference60 articles.

1. Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040

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