Reviving old protecting group chemistry for site-selective peptide–protein conjugation

Author:

Gunnoo Smita B.12345,Iyer Abhishek12345,Vannecke Willem12345,Decoene Klaas W.12345,Hebbrecht Tim67834ORCID,Gettemans Jan67834,Laga Mathias910115,Loverix Stefan910115,Lasters Ignace910115,Madder Annemieke12345ORCID

Affiliation:

1. OBCR Group

2. Dept. of Organic and Macromolecular Chemistry

3. Ghent University

4. Ghent

5. Belgium

6. Nanobody Lab

7. Dept. of Biochemistry

8. Faculty of Medicine and Health Sciences

9. Complix NV

10. Bioville

11. Diepenbeek

Abstract

Unprotected peptides equipped with property enhancing moieties and a Cys(Scm) residue can be site-selectively conjugated to proteins via crossed-disulfide formation.

Funder

Fonds Wetenschappelijk Onderzoek

Bijzonder Onderzoeksfonds

Agentschap Innoveren en Ondernemen

Universiteit Gent

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3