Amelioration effects ofCirsium japonicumvar.maackiiextract/fractions on amyloid beta25–35-induced neurotoxicity in SH-SY5Y cells and identification of the main bioactive compound
Author:
Affiliation:
1. Department of Food Science and Nutrition & Kimchi Research Institute
2. Pusan National University
3. Busan 46241
4. Republic of Korea
5. Department of Plant Science and Technology
6. Chung-Ang University
7. Anseong 17546
Abstract
Amyloid beta (Aβ) is a neurotoxic peptide, and the accumulation of Aβ in the brain is the major characteristic of Alzheimer's disease (AD).
Funder
National Research Foundation of Korea
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2020/FO/D0FO01041C
Reference90 articles.
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4. Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease
5. Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
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