Amelioration effects ofCirsium japonicumvar.maackiiextract/fractions on amyloid beta25–35-induced neurotoxicity in SH-SY5Y cells and identification of the main bioactive compound

Author:

Kim Min Jeong1234,Kim Ji-Hyun1234,Kim Ji Hyun1234,Lee Sanghyun5674ORCID,Cho Eun Ju1234ORCID

Affiliation:

1. Department of Food Science and Nutrition & Kimchi Research Institute

2. Pusan National University

3. Busan 46241

4. Republic of Korea

5. Department of Plant Science and Technology

6. Chung-Ang University

7. Anseong 17546

Abstract

Amyloid beta (Aβ) is a neurotoxic peptide, and the accumulation of Aβ in the brain is the major characteristic of Alzheimer's disease (AD).

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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