Influence of cyclic and acyclic cucurbiturils on the degradation pathways of the chemical warfare agent VX-Reference-Cited by-同舟云学术

Influence of cyclic and acyclic cucurbiturils on the degradation pathways of the chemical warfare agent VX

Published:2020 Issue:27 Volume:18 Page:5218-5227
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Andrae Beatrice¹²³⁴⁵,Bauer Daniel¹²³⁴⁵,Gaß Patrick¹²³⁴⁵,Koller Marianne⁶⁷⁸⁵,Worek Franz⁶⁷⁸⁵^ORCID,Kubik Stefan¹²³⁴⁵^ORCID

Affiliation:

1. Technische Universität Kaiserslautern

2. Fachbereich Chemie - Organische Chemie

3. Erwin-Schrödinger-Straße

4. 67663 Kaiserslautern

5. Germany

6. Institut für Pharmakologie und Toxikologie der Bundeswehr

7. Neuherbergstraße 11

8. 80937 München

Abstract

Cucurbit[7]uril and an acyclic cucurbituril cause the chemical warfare agent VX to preferentially decompose in basic aqueous solution under C–S bond cleavage rather than by the normally preferred hydrolysis of the P–O and P–S bonds.

Funder

Bundesministerium der Verteidigung

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01167C

Reference72 articles.

1. R. Black , in: Chemical Warfare Toxicology , ed. F. Worek , J. Jenner and H. Thiermann , RSC , Cambridge , 2016 , vol. 1 , pp. 1–28

2. In vitro and in vivo toxicological studies of V nerve agents: Molecular and stereoselective aspects

3. Organophosphate poisoning

4. H. John , F.Balszuweit , K.Kehe , F.Worek and H.Thiermann , in Handbook of Toxicology of Chemical Warfare Agents , ed. R. C. Gupta , Academic Press , New York , 2015 , pp. 817–874

5. The Use of Chemical Weapons in the Syrian Conflict

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