Sensitive SERS detection of oral squamous cell carcinoma-related miRNAs in saliva <i>via</i> a gold nanohexagon array coupled with hybridization chain reaction amplification-Reference-Cited by-同舟云学术

Sensitive SERS detection of oral squamous cell carcinoma-related miRNAs in saliva via a gold nanohexagon array coupled with hybridization chain reaction amplification

Published:2022 Issue:44 Volume:14 Page:4563-4575
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Wang Youwei¹,Zhang Yatong²,Du Qiu¹,Cao Demao¹,Lu Xiaoxia³,Meng Zhibing⁴^ORCID

Affiliation:

1. Department of Neurosurgery, Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu, 225000, China

2. Graduate School of Dalian Medical University, Dalian, Liaoning, 116011, China

3. Department of Oncology, Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu, 225000, China

4. Department of Oral and Maxillofacial Surgery, Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu, 225000, China

Abstract

Schematic diagram of HCR amplification strategy for the detection of miRNAs. (A) The preparation process of AuNHs array. (B) Synthesis of SERS probes (C) HCR process and SERS detection of miR-31 and miR-21.

Funder

National Natural Science Foundation of China

Natural Science Research of Jiangsu Higher Education Institutions of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AY/D2AY01180H

Reference37 articles.

1. MicroRNA-31: a pivotal oncogenic factor in oral squamous cell carcinoma

2. The role of differentially expressed salivary microRNA in oral squamous cell carcinoma. A systematic review