Post-translational modifications soften vimentin intermediate filaments-Reference-Cited by-同舟云学术

Post-translational modifications soften vimentin intermediate filaments

Published:2021 Issue:1 Volume:13 Page:380-387
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Kraxner Julia¹²³⁴,Lorenz Charlotta¹²³⁴,Menzel Julia⁵⁶⁷⁴,Parfentev Iwan⁸⁹³⁴,Silbern Ivan⁸⁹³⁴¹⁰^ORCID,Denz Manuela¹²³⁴,Urlaub Henning⁸⁹³⁴¹⁰,Schwappach Blanche⁵⁶⁷⁴¹¹,Köster Sarah¹²³⁴¹¹^ORCID

Affiliation:

1. Institute for X-Ray Physics

2. University of Göttingen

3. 37077 Göttingen

4. Germany

5. Department of Molecular Biology

6. University Medical Center Göttingen

7. 37073 Göttingen

8. Bioanalytical Mass Spectrometry

9. Max Planck Institute for Biophysical Chemistry

10. Bioanalytical Group

11. Cluster of Excellence “Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells” (MBExC)

Abstract

We mechanically tested partially phosphorylated vimentin intermediate filaments using optical traps and found that the additional charges considerably soften the filaments.

Funder

Horizon 2020 Framework Programme

Deutsche Forschungsgemeinschaft

Studienstiftung des Deutschen Volkes

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D0NR07322A

Reference39 articles.

1. Cytoskeletal crosstalk: when three different personalities team up