Development of a tissue construct with spatially controllable stiffnessviaa one-step 3D bioprinting and dual-crosslinking process

Author:

Pagnotta Giorgia1,Becconi Maila1ORCID,Malferrari Marco1ORCID,Aiello Donatella2ORCID,Napoli Anna2ORCID,Di Lisa Luana1,Grilli Stefano1,Rapino Stefania13ORCID,Focarete Maria Letizia13ORCID

Affiliation:

1. Department of Chemistry “Giacomo Ciamician” and INSTM UdR of Bologna, University of Bologna, 40126 Bologna, Italy

2. Department of Chemistry and Chemical Technologies, University of Calabria, Rende 87036, Italy

3. Health Sciences and Technologies - Interdepartmental Center for Industrial Research (HST-ICIR), Alma Mater Studiorum - Università di Bologna, 40064 Ozzano dell’Emilia, Bologna, Italy

Abstract

AlgMa bioink obtainedviaa green synthetic route and a dual crosslinking process is characterized by rheology to study the effect of crosslinking on cell viability and to fabricate bioprinted tissue models with spatially controlled stiffness.

Funder

Ministero dell'Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Chemistry (miscellaneous)

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