Multifunctional biocompatible Ni/Ni–P nanospheres for anti-tumor “neoadjuvant phototherapy” combining photothermal therapy and photodynamic therapy

Author:

Song Peizhe1,Jin Shujuan2,Cao Yue3,Zhang Shaopeng1ORCID,Yin Na45,Zhang Hao45,Wang Daguang1ORCID

Affiliation:

1. Department of Gastrocolorectal Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun 130021, China

2. Senior Department of General Surgery, The First Medical Center of Chinese PLA General Hospital, Fuxin Road, No. 28, Haidian District, Beijing, 100853, China

3. Department of Neurosurgery, The First Hospital of Jilin University, Changchun 130021, China

4. State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, P. R. China

5. School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China

Abstract

Multifunctional Ni/Ni-P/PEI/ICG nanoplatform can serve as “neoadjuvant phototherapy” combining photodynamic and photothermal therapy, and contrast agent for magnetic resonance imaging, which allows for both treatment and diagnosis.

Funder

National Natural Science Foundation of China

Major International Joint Research Programme

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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