Suzuki coupling-based synthesis of VATPase inhibitor archazolid natural product derived fragments-Reference-Cited by-同舟云学术

Suzuki coupling-based synthesis of VATPase inhibitor archazolid natural product derived fragments

Published:2019 Issue:55 Volume:9 Page:32210-32218
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Vincent Cooper T.¹²³⁴,Long Evan T.¹²³⁴,Jones Holly C.¹²³⁴,Young Jeffrey C.⁵²³⁴,Spiegel P. Clint¹²³⁴,O'Neil Gregory W.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Western Washington University

3. Bellingham

4. USA 98229

5. Department of Biology

Abstract

An archazolid natural product fragment that displays dose-dependent inhibition of the vacuolar-type ATPase (VATPase) has been synthesized by a high-yielding Suzuki coupling of two complex subunits.

Funder

Camille and Henry Dreyfus Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA07050H

Reference35 articles.

1. Synthesis of the C1–C23 Fragment of the Archazolids and Evidence for V-ATPase but not COX Inhibitory Activity

2. V-ATPase inhibition overcomes trastuzumab resistance in breast cancer

3. Up-regulation of cholesterol associated genes as novel resistance mechanism in glioblastoma cells in response to archazolid B

4. Anti-leukemic effects of the V-ATPase inhibitor Archazolid A

5. Vacuolar-ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Modular Total Synthesis of iso-Archazolids and Archazologs;The Journal of Organic Chemistry;2021-07-23

2. Correction: Suzuki coupling-based synthesis of VATPase inhibitor archazolid natural product derived fragments;RSC Advances;2019