Galectin-targeting glycocalix[4]arenes can enter the cells-Reference-Cited by-同舟云学术

Galectin-targeting glycocalix[4]arenes can enter the cells

Published:2023 Issue:69 Volume:59 Page:10404-10407
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Vlachová Miluše¹^ORCID,Tran Van Nguyen²,Červený Jakub¹³,Dolníček František²,Petrásková Lucie¹,Pelantová Helena¹,Kundrát Ondřej²,Cvačka Josef⁴^ORCID,Bosáková Zuzana³,Křen Vladimír¹^ORCID,Lhoták Pavel²,Viktorová Jitka²,Bojarová Pavla¹⁵^ORCID

Affiliation:

1. Laboratory of Biotransformation, Institute of Microbiology of the Czech Academy of Sciences, Vídeňská 1083, CZ-14220, Praha 4, Czech Republic

2. University of Chemistry and Technology Prague, Technická 5, CZ-16628 Praha 6, Czech Republic

3. Department of Analytical Chemistry, Faculty of Science, Charles University in Prague, Hlavova 8, CZ-12843 Praha 2, Czech Republic

4. Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo nám. 2, CZ-16610 Praha 6, Czech Republic

5. Department of Health Care Disciplines and Population Protection, Faculty of Biomedical Engineering, Czech Technical University in Prague, nám. Sítná 3105, CZ-27201 Kladno, Czech Republic

Abstract

Multivalent high-affinity glycocalix[4]arenes carrying a coumaryl-substituted glycomimetic can enter epithelial cells and are able to modulate the expression of galectin-3.

Funder

Ministerstvo Školství, Mládeže a Tělovýchovy

Grantová Agentura České Republiky

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC02905K

Reference31 articles.

1. Achieving High Affinity towards a Bacterial Lectin through Multivalent Topological Isomers of Calix[4]arene Glycoconjugates

2. Selectivity of original C-hexopyranosyl calix[4]arene conjugates towards lectins of different origin

3. Glycoclusters presenting lactose on calix[4]arene cores display trypanocidal activity

4. Synthesis of lactosylated glycoclusters and inhibition studies with plant and human lectins

5. Calix[n]arene‐Based Glycoclusters: Bioactivity of Thiourea‐Linked Galactose/Lactose Moieties as Inhibitors of Binding of Medically Relevant Lectins to a Glycoprotein and Cell‐Surface Glycoconjugates and Selectivity among Human Adhesion/Growth‐Regulatory Galectins

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