Unveiling Amaryllidaceae alkaloids: from biosynthesis to antiviral potential

Unveiling Amaryllidaceae alkaloids: from biosynthesis to antiviral potential – a review

Published:2024 Issue: Volume: Page:
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Jayawardena Thilina U.¹^ORCID,Merindol Natacha¹^ORCID,Liyanage Nuwan Sameera¹^ORCID,Desgagné-Penix Isabel¹²^ORCID

Affiliation:

1. Department of Chemistry, Biochemistry, and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, QC, G8Z 4M3, Canada

2. Plant Biology Research Group, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada

Abstract

Amaryllidaceae alkaloids (AAs) are a unique class of specialized metabolites containing heterocyclic nitrogen bridging that play a distinct role in higher plants.

Funder

Natural Sciences and Engineering Research Council of Canada

Canada Research Chairs

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NP/D3NP00044C

Reference134 articles.

1. Cytotoxicity and Antiviral Properties of Alkaloids Isolated from Pancratium maritimum

2. A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors

3. Chemical Synthesis and Biological Activities of Amaryllidaceae Alkaloid Norbelladine Derivatives and Precursors

4. Identification of SARS-CoV-2 inhibitors targeting Mpro and PLpro using in-cell-protease assay

5. Biological Investigation of Amaryllidaceae Alkaloid Extracts from the Bulbs of Pancratium trianthum Collected in the Senegalese Flora

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