Life cycle analysis and sustainability comparison of reversed phase high performance liquid chromatography and carbon dioxide-containing chromatography of small molecule pharmaceuticals-Reference-Cited by-同舟云学术

Life cycle analysis and sustainability comparison of reversed phase high performance liquid chromatography and carbon dioxide-containing chromatography of small molecule pharmaceuticals

Published:2022 Issue:11 Volume:24 Page:4516-4532
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Fitch Brian N.¹^ORCID,Gray Rebekah¹^ORCID,Beres Martin²^ORCID,Hicks Michael B.³^ORCID,Farrell William⁴^ORCID,Aurigemma Christine⁵^ORCID,Olesik Susan V.¹^ORCID

Affiliation:

1. The Ohio State University, Department of Chemistry and Biochemistry, Columbus, Ohio, USA

2. Bristol Myers Squibb, Separation and Analysis Technology Team, Lawrenceville, New Jersey, USA

3. Merck & Co. Inc., Rahway, New Jersey, USA

4. Pfizer Global Research and Development, Medicinal Chemistry, Groton, California, USA

5. Pfizer Global, Oncology Medicinal Chemistry, San Diego, California, USA

Abstract

Life cycle analysis allows comparison of RP-HPLC to SFC.

Funder

American Chemical Society

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/GC/D1GC03750A

Reference23 articles.

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2. S.Slater , M.Savelski , W.Carole and D. J. C.Constable , in Green Chemistry in the Pharmaceutical Industry , ed. P. Dunn , A. Wells and M. Williams , Wiley-VCH Verlag GmbH & Co., Struass GmbH , Mörlenbach , 2010 , pp. 49–82

3. HPLC-EAT (Environmental Assessment Tool): A tool for profiling safety, health and environmental impacts of liquid chromatography methods

4. Analytical Method Volume Intensity (AMVI): A green chemistry metric for HPLC methodology in the pharmaceutical industry

5. Assessing Safety, Health, and Environmental Impact Early during Process Development

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